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DeficienciesOct 22, 2026 · 4 min read

You are anemic. That is the beginning of the question, not the answer

Around a third of men and postmenopausal women who turn up with iron deficiency anaemia have an underlying condition causing it, most often in the gut. Iron tablets without finding the cause is bailing out a boat without looking for the leak.

If a blood test comes back showing anemia, the natural reading is that you have found the problem. Iron tablets, recheck in a few months, done.

That is sometimes right. It is also, for a meaningful minority of people, the moment the actual question starts, and the one most likely to be skipped.

Anemia is a symptom

Running out of iron is not something a healthy body does on its own. Iron goes down for a reason, and there are only really two: you are not taking enough in, or you are losing it somewhere.

The second is the one that matters. Losing iron means bleeding, and bleeding that is slow enough to go unnoticed is precisely the kind that drains stores over months without producing a single dramatic symptom.

What the guidelines actually say

This is not a fringe concern. The British Society of Gastroenterology's guideline on iron deficiency anaemia in adults states that roughly a third of men and postmenopausal women presenting with iron deficiency anaemia turn out to have an underlying condition causing it, most commonly somewhere in the gastrointestinal tract.

For that group the guideline's recommendation is direct: gastroscopy and colonoscopy should generally be the first-line investigations in men and postmenopausal women with newly diagnosed iron deficiency anaemia. Not watchful waiting, and not iron alone.

It also recommends routinely screening everyone for coeliac disease, which turns up in 3 to 5% of iron deficiency anaemia cases and which causes the deficiency by stopping absorption rather than by bleeding.

One further detail worth knowing, because it removes a reason to delay: the guideline says iron replacement should not be deferred while you wait for those investigations. Starting the iron and finding the cause are not alternatives.

If you are premenopausal, this reads differently

For somebody with periods, heavy menstrual bleeding is by far the most common explanation, and the investigations above are usually not the first step.

But "it is probably your periods" deserves one question rather than none, because heavy bleeding is itself routinely normalised. Soaking through protection hourly, passing clots larger than a coin, bleeding longer than a week, or periods that stop you doing ordinary things are not simply what some people get. They are a treatable thing that is also draining your iron, and treating the bleeding is often what stops the anemia coming back.

Why this belongs on a mental health site

Three reasons, and the first two are the ones people live.

The waiting is its own event. Being told you need a camera test, and then waiting for it, is frightening in a specific way, and the fear is not irrational. Most of those investigations find nothing serious. That genuinely is the likeliest outcome. It does not make the weeks beforehand comfortable, and anybody telling you not to worry is asking for something you cannot simply decide to do.

An uninvestigated cause means it comes back. Iron tablets against an unfixed source of loss is bailing without finding the leak. People go through this cycle repeatedly, feel better, slide back, and conclude that their exhaustion must be depression after all.

The symptoms overlap with anxiety almost completely, which is how this gets missed in the first place. That overlap, and how to tell them apart, is here.

The state of the evidence is shifting

Worth knowing if you are being told your numbers are fine. The American Society of Hematology's 2026 diagnostic guidelines set out to cover diagnosing iron deficiency whether or not anemia is present, and say in their own abstract that the diagnostic guidance preceding them was limited and not evidence based.

That is an unusually blunt thing for a professional body to say, and it is useful context for anyone who has been told a borderline result is nothing. The thresholds themselves are being actively revised, so a "normal" from a few years ago is not necessarily a normal now.

What to take from this

If you have been told you are anemic, two questions are worth asking out loud:

"Do we know why?"

"Does my age and situation mean I should be investigated for a cause?"

The line the guideline draws is about menstruation rather than gender, and it is worth understanding that way round. If you are not losing blood every month, there is no ordinary explanation for where the iron went, which is the whole reason the investigations are recommended.

So if you do not menstruate and nobody has mentioned a gastroscopy or a colonoscopy, that is the thing to ask about by name. If you do menstruate and the answer is your periods, the better question is whether the bleeding itself can be treated, because treating it is usually what stops the anaemia returning.

Most of the time this ends with a dull and reassuring answer. The point is to get the answer rather than assume it.

Mura is not a doctor and cannot order a test or interpret your results. If your symptoms are severe, or you have black or bloody stools, that is a same-day conversation with a clinician rather than a reading task.

This article is for general information and is not a substitute for professional care. If you are in crisis or thinking about harming yourself, please contact your local emergency services or a crisis line. See crisis lines.

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